The research group led by Dr. José Manuel Martín García specializes in the study of protein structure and dynamics using advanced serial crystallographic techniques. We use synchrotron radiation sources and XFELs to investigate fundamental biological processes, such as antibiotic resistance and the mechanisms of certain diseases. Our work has contributed to the development of innovative methods for protein crystallization, as well as the design of sample delivery devices for high-resolution experiments. This research has applications in biomedicine and the development of new drugs.

 

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Research Lines

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1. Time-resolved serial crystallography at synchrotrons and X-ray free-electron lasers (XFELs).

2. Dynamic studies of biomedical processes, including cancer mechanisms and antibiotic resistance.

3. Development of new methodologies for protein crystallization, optimizing the production of nanocrystals.

4. Design and improvement of devices for crystalline sample delivery in XFEL and synchrotron experiments.